Fibrinolytic Therapy Market Growth Accelerated by Adoption of Tissue Plasminogen Activators



 Fibrinolytic therapy helps in dissolving of blood clots and restores normal blood flow. It involves use of medications like tissue plasminogen activator (tPA) that catalyzes the conversion of plasminogen to plasmin. Plasmin then degrades fibrin clots and thereby opens blocked arteries and veins. These agents are gaining significance in treatment of ischemic stroke, pulmonary embolism and myocardial infarction.

 The global Fibrinolytic Therapy Market is estimated to be valued at US$ 34 billion in 2024 and is expected to exhibit a CAGR of 3.7% over the forecast period from 2023 to 2030, as highlighted in a new report published by Coherent Market Insights.

Market key trends:
The growth of fibrinolytic therapy market is majorly driven by increasing adoption of tissue plasminogen activators globally. Tissue plasminogen activators hold the dominant share of this market as they are the preferred fibrinolytic drugs over streptokinase. Their use has significantly improved treatment outcomes of disorders like myocardial infarction and stroke. Additionally, they exhibit greater specificity for fibrin breakdown and cause minimal risks of bleeding. Their efficacy and safety attributes have led to an increasing preference among healthcare professionals for managing thrombotic conditions. This rising demand for tissue plasminogen activators is a key trend that is promoting the expansion of global fibrinolytic therapy market during the forecast period.

Segment Analysis
The global fibrinolytic therapy market is dominated by tenecteplase and alteplase segments. Among these, the tenecteplase segment accounts for the largest share owing to higher effectiveness and lower risk of bleeding compared to alteplase. Tenecteplase has shown to achieve higher rate of early patency of occluded coronary arteries in treating heart attacks.

Key Takeaways
The global fibrinolytic therapy market is expected to witness high growth over the forecast period of 2023 to 2030.

The North America region currently dominates the market and is expected to grow at a CAGR of 2.5% during the forecast period. This can be attributed to the growing prevalence of cardiovascular diseases, aging population, and developed healthcare infrastructure in the region.

Key players operating in the fibrinolytic therapy market are Merck & Co., Genentech, Roche, Boehringer Ingelheim Pharmaceuticals Inc, Sedico Pharmaceutical Company among others. Merck & Co. recently received approval for its tenecteplase drug TNKase for treatment of heart attack. The drug has shown superiority over existing drugs with faster clearance of blood clots and lower bleeding complications. 

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